6 (1.2-5.8) and 2.5 (1.3-5.2), respectively), whereas levetiracetam intake reduces the risk of nonadherence (OR 0.5 [0.2-0.9]).
The prevalence of AED adherence was 70.8%. Education level and having a seizure in the last 6 months were significant predictors of nonadherence, whereas levetiracetam intake reduces the risk of nonadherence.
The prevalence of AED adherence was 70.8%. Education level and having a seizure in the last 6 months were significant predictors of nonadherence, whereas levetiracetam intake reduces the risk of nonadherence.There has been a long-standing belief that generic drugs are of lower value in comparison to their branded name counterparts. They are in particular under scrutiny due to their low market price. Even though the reduction in costs is largely based on skipping expensive preclinical studies and clinical trials for generic drugs, the purity and quality of the raw materials in the production of generic drugs is debatable. Thus, the objective of the study was to analyze and assess the quality comparability of generic furosemide 40 mg (FSD) tablets to branded product available in the market.
Quality control tests, in vitro drug release assessments, and thermal analysis investigations for both analog products of FSD were performed. https://www.selleckchem.com/products/triton-tm-x-100.html Various physical parameters related to the tablet quality, such as hardness, weight variation, and friability tests, were examined. In vitro drug release behavior evaluations were conducted according to United States Pharmacopeia (USP) specifications and guidelines, whereas thermal anapectroscopic analysis to confirm potential hidden variations between generic and branded products that could not be obtained by the bioequivalence studies.This study was aimed at exploring the intentions of clinical pharmacy students to be involved in clinical research, and to identify the perceived and existing barriers to conducting research activities in the Eastern region of Saudi Arabia.
This was a cross-sectional questionnaire survey.
This study was conducted between February and March 2019, in the Eastern region of Saudi Arabia, using clinical pharmacy students at the two universities that offer a pharmacy program there (King Faisal University and Imam Abdulrahman bin Faisal University). An electronic questionnaire tool was adapted to explore the intentions of and barriers to carry out medical research among the students.
Descriptive statistics are presented as frequencies and percentages. A χtest was used to explore any statistically significant difference between the student demographics and the intentions and barriers regarding medical research. ? 0.05 was considered statistically significant.
Only 35.1% (= 33) of the participating clinical pharmacy students had previous research experience. Of these, the majority encountered barriers to medical research (81.8%, = 27). The most commonly reported barriers were a lack of funding, a lack of support from the college for research activities, and difficulties in coordination between the research team. Around 36.2% (= 34) of the participants were currently involved in research activities, with a majority of them (67.6%, = 23) spending an average of 5?h or less per week for research.
Our study highlights that the intention among clinical pharmacy students to carry out medical research was poor. Educational institutions are advised to provide more financial and logistic support to their medical researchers.
Our study highlights that the intention among clinical pharmacy students to carry out medical research was poor. Educational institutions are advised to provide more financial and logistic support to their medical researchers.The wide availability of medications has led to an increased exposure of humans to the possibility of poisoning. An unavoidable effect due to the availability of these medications has also led to a rising increment in the number of poisoning cases. All drugs, especially when administered in large doses or overextended periods, can initiate a toxic condition. Therefore, the objective of this study was to examine nationwide, the patterns attributed to poisoning, and to describe the sociodemographic, and geographic distribution of poisoning, by identifying the category of substances implicated in these cases.
A retrospective study based on telephone calls reported on poisoning caused by pharmaceutical products undertaken by the National Poisoning Centre (NPC) in Penang (Malaysia) was used as the basis of this study covering the period between 2010 and 2015. The study included the mode and type of poisoning, exposure routes as well as the incidence locations.
A total of 10,998 cases were examined, finding trising incidence of poisoning. As such, analyzing the trends in poisoning in a particular zone periodically could help health policy-makers to develop management policies and prevention strategies.The aim of this study was to evaluate the possibility of using visceral adiposity index (VAI), serum leptin, and lipid profile as indicators of impaired glucose tolerance in Iraqi obese patients.
A cross-sectional study was performed in Iraqi obese patients of both sexes. Body mass index (BMI), waist circumference, hip circumference, triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), VAI, waist-to-hip ratio (WHR), serum leptin, and 2-h glucose tolerance test (2-h GT) were determined and compared with those of healthy non-obese control group. A correlation analysis was performed to determine the strength of association between the studied markers. Data were adjusted to determine gender differences in this regard.
Kolmogorov-Smirnov, Shapiro-Wilk analyses, Mann-Whitney test, and unpaired test were used for the two-group comparisons once applicable. Pearson's and Spearman's correlation analyses were used to measure the relationship levels between the studied variables.
A total of 144 obese patients were included; the mean age was 37.11 ± 8.2 years and 92 (63.9%) were females. Compared with non-obese subjects, the participants had significantly higher levels of BMI, WC, WHR, VAI, TG, leptin, and 2-h GTObese male subjects had significantly higher values of body weight, WC, HC, VAI, and TG compared with obese females. Elevated 2-h GT was significantly associated with VAI (= 0.291, = 0.0004), TG (= 0.319, = 0.0001), and LDL-C/HDL-C ratio (= 0.435, &lt; 0.0001) in the obese patients only.
The results provide evidence that VAI, TG, and LDL-C/HDL-C ratio can be suggested as potential markers for the risk assessment of impaired glucose tolerance in Iraqi obese patients.
The results provide evidence that VAI, TG, and LDL-C/HDL-C ratio can be suggested as potential markers for the risk assessment of impaired glucose tolerance in Iraqi obese patients.